Author

Debra J. Lett

Newcastle University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam R. SmithiD· 1 shared Andrew RobinsoniD· 1 shared Darren M. SoanesiD· 1 shared Delphine BocheiD· 1 shared Ehsan PishvaiD· 1 shared Giulia PegoraroiD· 1 shared Isabel CastanhoiD· 1 shared Jennifer L. ImmiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adam R. SmithORCID

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1 paper

Recent·Most cited

Systemic infections alter cortical transcriptional signatures in Alzheimer's disease

Giulia Pegoraro, Lachlan Ford MacBean, Adam R. Smith, Darren M. Soanes, Rebecca G. Smith, Jennifer L. Imm, Joshua Harvey, Morteza P Kouhsar, Valentin Laroche, Luke Stephen Weymouth, Isabel Castanho, Winston Hide, Laura Palmer, Debra J. Lett, Andrew Robinson, , Katie Lunnon

This study examines how systemic respiratory infections alter transcriptional patterns in the Alzheimer's disease brain, identifying gene expression changes and pathways linked to immune and vascular responses.

Neurobiology of Aging · Jun 26, 2026Peer-reviewedNeuroscience