Author

Denny Yang

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Gabriel BalmusiD· 2 shared Kangning He· 2 shared Thomas VogtiD· 2 shared A.L. Bergander· 1 shared Alexander Vogt· 1 shared Anastasia IllarionovaiD· 1 shared Annette GärtneriD· 1 shared Brinda C. PrasadiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

Gabriel BalmusORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Prime editing enables high-throughput identification and characterization of selective MutSβ inhibitors

Yangwode Jing, Jun Yan, Denny Yang, Yanjin Chen, Issam Senoussi, James Woodward, Katya Williams, Hahn Kim, Kangning He, Herwin Daub, Vinay Dahiya, Maren Thomsen, Jia Ling, Purnima Ravisankar, Yuri Pritykin, , Britt Adamson

This study uses prime editing to identify and characterize MutSβ inhibitors that reduce (CAG)n repeat expansion.

bioRxiv · Oct 6, 2026 · PreprintBioengineering

Unscheduled DNA synthesis reveals a DNA repair hotspot and biomarker of somatic instability at the expanded-CAG repeat tract in the huntingtin gene

Judith Praena Fernandez, Annette Gärtner, Jesús Pérez‐Pérez, Sarah A. Cumming, Jia Feng, Katherine Van Belois, Kangning He, Denny Yang, Carla Castells-Esteve, Maria Bergé-Gardeñes, A.L. Bergander, Krzysztof P. Lubieniecki, Mihai Miclăuș, Nicolás Fissolo, Manuel Comabella, , Paolo Beuzer

The paper develops URSA, a method to quantify DNA repair activity at the CAG repeat tract in HD, showing it correlates with somatic instability and can be measured rapidly in blood cells.

bioRxiv · Jul 29, 2026 · PreprintNeuroscience