Author

María C. Ramos

Fundación MedinaORCID 0000-0002-3674-615XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandro Rodríguez MartíneziD· 2 shared Horacio Pérez‐SáncheziD· 2 shared Irene LuqueiD· 2 shared Olga GenilloudiD· 2 shared Rosario Fernández‐GodinoiD· 2 shared Alžběta SrovnalováiD· 1 shared AM MadureiraiD· 1 shared Ana Belén Arroyo-Rodríguez· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

Alejandro Rodríguez MartínezORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BODIPY-Tagged β-Lactams as Selective Quenched Activity-Based Probes to Target Human Neutrophil Elastase

Rita Félix, Luís A. R. Carvalho, Ismael Rufino, Rita Cardoso Guedes, AM Madureira, Ana Mallo‐Abreu, Lídia Gonçalves, Olga Genilloud, Rosario Fernández‐Godino, María C. Ramos, Rui Moreira

This study develops quenched activity-based probes (qABPs) using β-lactam cores to selectively detect human neutrophil elastase in live cells.

RSC Chemical Biology · Jan 1, 2026Peer-reviewedPharmacology & Toxicology

Discovery of Z1362873773: A Novel Fascin Inhibitor from a Large Chemical Library for Colorectal Cancer

Alejandro Rodríguez Martínez, Lucía Giraldo-Ruiz, María C. Ramos, Irene Luque, Diogo Ribeiro, Fátima Postigo-Corrales, Begoña Alburquerque-González, Silvia Montoro‐García, Ana Belén Arroyo-Rodríguez, Pablo Conesa‐Zamora, Ana María Hurtado, Ginés Luengo‐Gil, Horacio Pérez‐Sánchez

The paper identifies a novel fascin inhibitor, Z1362873773, from a chemical library that inhibits cancer cell migration and shows potential as a colorectal cancer treatment.

Scientific Reports · Apr 28, 2025Peer-reviewedCancer Biology

Morphological Profiling Dataset of EU-OPENSCREEN Bioactive Compounds Over Multiple Imaging Sites and Cell Lines

Christopher Wolff, Martin Neuenschwander, Carsten Jörn Beese, Divya Sitani, María C. Ramos, Alžběta Srovnalová, María José Varela, Павел Геннадьевич Полищук, Katholiki Skopelitou, Ctibor Škuta, Bahne Stechmann, Jose Manuel Brea, Mads H. Clausen, Petr Džubák, Rosario Fernández‐Godino, , Christopher Schmied

The paper presents a morphological profiling dataset of EU-OPENSCREEN bioactive compounds across multiple imaging sites and cell lines, validated for robustness and used to map profiles to activity and toxicity.

iScience · Apr 17, 2025Peer-reviewedCell Biology

Exploring the druggability of the UEV domain of human TSG101 in search for broad-spectrum antivirals

Fernando Montero, Marisa Parra‐López, Alejandro Rodríguez Martínez, Javier Murciano‐Calles, Pedro Buzón, Ziying Han, Lian‐Yu Lin, María C. Ramos, Javier Ruiz‐Sanz, José C. Martínez, Marco Radi, Christiane Moog, Sandra Diederich, Ronald N. Harty, Horacio Pérez‐Sánchez, , Irene Luque

This study identifies drug-like inhibitors that block TSG101-UEV/PTAP interactions, impairing viral budding and replication across multiple virus families.

Protein Science · Dec 26, 2024Peer-reviewedMolecular Biology