Author

Dongdong Xu

Chinese Academy of SciencesPrimary ORCID profile (0000-0002-6935-9375 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Dongdong XuiD1 paper · Zhejiang Wanli University

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Guoping FengiD· 1 shared Jianbang LiniD· 1 shared Jonathan J. WildeiD· 1 shared Lixin YangiD· 1 shared Mengqi LiiD· 1 shared Peimin Qi· 1 shared Tomomi AidaiD· 1 shared Yuanyuan Hou· 1 shared

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2020-2020 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Guoping FengORCID

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1 paper

Recent·Most cited

Prime editing primarily induces undesired outcomes in mice

Tomomi Aida, Jonathan J. Wilde, Lixin Yang, Yuanyuan Hou, Mengqi Li, Dongdong Xu, Jianbang Lin, Peimin Qi, Zhonghua Lu, Guoping Feng

In mouse zygotes, prime editing installed 10 modifications across 6 genes, but undesired products such as large deletions outnumbered intended edits, traced to PE3 double-nicking.

bioRxiv · Aug 6, 2020 · PreprintMolecular Biology