Author

E. Bielczyk-Maczynska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 3 Physiology· 2

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. Li· 2 shared J. W. Knowles· 2 shared K. J. Svensson· 2 shared M. Zhao· 2 shared A. Dunn· 1 shared A. Rabiee· 1 shared A. Rao· 1 shared A. Shah· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

J. Li

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5 papers

Recent·Most cited

Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models

J. Li, C. Jin, S. Gustafsson, A. Rao, M. Wabitsch, C. Y. Park, T. Quertermous, E. Bielczyk-Maczynska, J. W. Knowles

The paper presents a single-cell RNA-sequencing dataset of human and mouse adipogenesis models, revealing three cell clusters during differentiation.

bioRxiv · Mar 27, 2023Cell Biology

G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

E. Bielczyk-Maczynska, M. Zhao, P.-J. H. Zushin, T. M. Schnurr, H.-J. Kim, J. Li, P. Nallagatla, P. Sangwung, C. Park, C. Cornn, A. Stahl, K. J. Svensson, J. W. Knowles

This study identifies GPR151 as a regulator of hepatic gluconeogenesis and links its dysfunction to type 2 diabetes risk.

bioRxiv · May 25, 2022Physiology

Phosphoproteomic mapping reveals distinct signaling actions and activation of protein synthesis and muscle hypertrophy by Isthmin-1

M. Zhao, N. B. Dannieskiold-Samsoee, L. Ulicna, Q. Nguyen, L. Voilquin, D. E. Lee, J. P. White, Z. Jiang, N. Cuthbert, S. Paramasivam, E. Bielczyk-Maczynska, C. Van Rechem, K. J. Svensson

This study identifies distinct phosphoproteomic effects of Ism1 compared to insulin, revealing novel pathways in muscle hypertrophy and protein synthesis.

bioRxiv · May 19, 2022Cell Biology

Flattening of diurnal glucocorticoid oscillations causes Cd36 and insulin-mediated obesity

S. Tholen, K. M. Kovary, A. Rabiee, E. Bielczyk-Maczynska, W. Yang, F. B. Kraemer, M. N. Teruel

This study shows that flattened diurnal glucocorticoid oscillations lead to obesity and diabetes by dysregulating lipid metabolism via Cd36 and insulin signaling in adipose tissues.

bioRxiv · Jan 2, 2020Physiology

Loss of adipocyte identity through synergistic repression of PPARγ by TGF-β and mechanical stress

E. Bielczyk-Maczynska, B. Taylor, C. Miller, M. L. Zhao, A. Shah, Z. Bahrami-Nejad, A. Dunn, M. Teruel

The paper shows that TGF-β and mechanical stress together repress PPARγ, causing adipocytes to lose identity and convert into myofibroblasts in a fibrosis model.

bioRxiv · Apr 11, 2019Cell Biology