Author

P.-J. H. Zushin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Stahl· 3 shared A. Banks· 1 shared A. I. Mina· 1 shared A. L. Gunawan· 1 shared A. M. Bertholet· 1 shared B. B. Kahn· 1 shared B. Liu· 1 shared B. Spiegelman· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersPhysiology

A. Stahl

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Author profile →

4 papers

Recent·Most cited

PhysiologybioRxivMay 25, 2022

G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

E. Bielczyk-Maczynska, M. Zhao, P.-J. H. Zushin…·J. W. Knowles

This study identifies GPR151 as a regulator of hepatic gluconeogenesis and links its dysfunction to type 2 diabetes risk.

DOI 10.1038/s41467-022-35069-9

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintMar 18, 2022

Coenzyme Q regulates UCP1 expression and thermogenesis through the integrated stress responses

C.-F. Chang, A. L. Gunawan, P.-J. H. Zushin…·A. Stahl

This study shows that CoQ deficiency in BAT activates the ISR and suppresses UCP1, yet increases whole-body metabolic rates and reduces weight gain on HFD.

DOI 10.1101/2022.03.18.484957

mousebulk RNA-seq

𝕏 PostBluesky

BiochemistrybioRxivAug 20, 2020

4 β-hydroxycholesterol is a pro-lipogenic factor that promotes SREBP1c expression and activity through Liver X-receptor.

O. Moldavski, P.-J. H. Zushin, C. A. Berdan…·R. Zoncu

This study identifies 4β-hydroxycholesterol as a pro-lipogenic factor that activates SREBP1c via LXR to promote de novo lipogenesis.

DOI 10.1016/j.jlr.2021.100051

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivJan 13, 2020

Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through Growth Differentiation Factor 3

J. A. Hall, D. Ramachandran, H. C. Roh…·A. Banks

This study shows that preventing PPARγ S273 phosphorylation reduces insulin resistance without weight gain or side effects, identifying Gdf3 as a key mediator.

DOI 10.1016/j.cmet.2020.08.016

mousebulk RNA-seq

𝕏 PostBluesky