Interactions of netrin-1 through its glycosylation sites immobilize Deleted in Colorectal Cancer (DCC) by favoring its constitutive clustering
K. Uriot, O. Blanc, N. Auduge, O. Faklaris, N. Chaverot, E. Bloch, N. Borghi, M. Coppey-Moisan, P. P. Girard
The paper investigates how netrin-1 glycosylation sites affect DCC clustering and mobility, showing they promote constitutive nanoclusters and reduce DCC movement.
bioRxiv · Oct 26, 2023 · PreprintCell Biology