O. Faklaris

Interactions of netrin-1 through its glycosylation sites immobilize Deleted in Colorectal Cancer (DCC) by favoring its constitutive clustering

The paper investigates how netrin-1 glycosylation sites affect DCC clustering and mobility, showing they promote constitutive nanoclusters and reduce DCC movement.

Structure and mechanics of the human Nuclear Pore Complex basket

The paper uses AFM and SMLM to show the human Nuclear Pore Complex basket is soft and conformationally flexible, enabling diverse cargo transport.

Long-term quality assessment and monitoring of light microscope performance through accessible and reliable protocols, tools and metrics

This paper develops automated protocols and metrics for long-term light microscope quality assessment and monitoring using accessible tools and an ImageJ plugin.

RNA labelling in live plants reveals single cell transcriptional dynamics: application to phosphate signaling

The paper uses RNA imaging in live Arabidopsis plants to study single-cell transcriptional dynamics, finding rapid transcriptional repression in response to phosphate and high intrinsic noise.

The PAXFOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition

This study shows PAXFOXO1 fusion proteins drive neural cells to become ARMS-like cells but are limited by G1 cell cycle arrest, which can be overcome by CYCLIN D1 or MYCN.