Author

E. C. Ralph

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Casimiro-Garcia· 1 shared A. Giddabasappa· 1 shared A. Pinto-Fernandez· 1 shared B. M. Kessler· 1 shared B. Yang· 1 shared C. W. Lee· 1 shared D. R. Healy· 1 shared F. Wang· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Casimiro-Garcia

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1 paper

Recent·Most cited

Human USP18 protects diverse cancer lineages from Type I Interferon independently of its canonical catalytic function

V. Jove, H. Wheeler, C. W. Lee, D. R. Healy, K. Levine, E. C. Ralph, B. Yang, A. Giddabasappa, P. Loria, M. Yamaguchi, A. Casimiro-Garcia, B. M. Kessler, A. Pinto-Fernandez, V. Frattini, P. D. Wes, F. Wang

This paper shows USP18's scaffold function, not its catalytic activity, is critical for inhibiting cancer growth and Type I interferon signaling in human cells.

bioRxiv · Mar 23, 2023 · PreprintCancer Biology