Author

A. Giddabasappa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Yang· 2 shared A. Atakilit· 1 shared A. Casimiro-Garcia· 1 shared A. Pinto-Fernandez· 1 shared B. C. Hann· 1 shared B. Liang· 1 shared B. M. Kessler· 1 shared B. Zirak· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

B. Yang

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2 papers

Recent·Most cited

Human USP18 protects diverse cancer lineages from Type I Interferon independently of its canonical catalytic function

V. Jove, H. Wheeler, C. W. Lee, D. R. Healy, K. Levine, E. C. Ralph, B. Yang, A. Giddabasappa, P. Loria, M. Yamaguchi, A. Casimiro-Garcia, B. M. Kessler, A. Pinto-Fernandez, V. Frattini, P. D. Wes, F. Wang

This paper shows USP18's scaffold function, not its catalytic activity, is critical for inhibiting cancer growth and Type I interferon signaling in human cells.

bioRxiv · Mar 23, 2023 · PreprintCancer Biology

Integrin αvβ8 on T cells is responsible for suppression of anti-tumor immunity in multiple syngeneic models and is a promising target for tumor immunotherapy

E. Dodagatta-Marri, H.-Y. Ma, B. Liang, J. Li, D. S. Meyer, K.-H. Sun, X. Ren, B. Zirak, M. D. Rosenblum, M. Headley, L. Pinzas, N. I. Reed, J. S. Del Cid, M. Adoumie, B. C. Hann, , D. Sheppard

This study shows that blocking integrin αvβ8 on T cells enhances anti-tumor immunity in multiple syngeneic models and is effective even when tumor cells do not express the integrin.

bioRxiv · May 14, 2020Cancer Biology