Author

D. Homann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

V. van der Heide· 5 shared B. Davenport· 4 shared K. Jhun· 4 shared F. Victorino· 3 shared J. Eberlein· 3 shared T. Nguyen· 3 shared A. L. Posgai· 1 shared A. Maayan· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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5 shared papersImmunology

V. van der Heide

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Author profile →

5 papers

Recent·Most cited

Functional impairment of "helpless" CD8+ memory T cells is transient and driven by prolonged but finite cognate antigen presentation

V. van der Heide, B. Davenport, B. Cubitt, V. Roudko, D. Choo, E. Humblin, K. Jhun, K. Angeliadis, T. Dawson, G. Furtado, A. O. Kamphorst, R. Ahmed, J. C. de la Torre, D. Homann

This study shows that helpless CD8+ memory T cells, which form without CD4+ help, have transient functional impairments due to prolonged antigen exposure, which resolve over time.

bioRxiv · Jan 22, 2024Immunology

ACE2 and SARS-CoV-2 Expression in the Normal and COVID-19 Pancreas

I. Kusmartseva, W. Wu, F. Syed, V. van der Heide, M. Jorgensen, P. Joseph, X. Tang, E. Candelario-Jalil, C. Yang, H. Nick, J. Harbert, A. L. Posgai, R. Lloyd, S. Cechin, A. Pugliese, , M. A. Atkinson

This study examines ACE2 and SARS-CoV-2 expression in normal and COVID-19 pancreas tissues, finding prominent ACE2 expression in ductal epithelium and microvasculature, with limited endocrine cell expression and no strong evidence of SARS-CoV-2 infection of endocrine cells.

bioRxiv · Aug 31, 2020 · PreprintPathology

Chemokine Signatures Of Pathogen-Specific T Cells I: Effector T Cells

J. Eberlein, B. Davenport, T. Nguyen, F. Victorino, K. Jhun, V. van der Heide, M. Kuleshov, A. Maayan, R. Kedl, D. Homann

This study defines the chemokine profiles of pathogen-specific effector T cells and identifies their temporospatial organization and regulatory mechanisms.

bioRxiv · Feb 5, 2020Immunology

Aging Boosts Antiviral CD8+T Cell Memory Through Improved Engagement Of Diversified Recall Response Determinants

B. Davenport, J. Eberlein, T. Nguyen, F. Victorino, K. Jhun, H. Abuirqeba, V. van der Heide, P. Heeger, D. Homann

This study shows that aging enhances CD8+ memory T cell recall responses by utilizing diverse molecular mechanisms, supporting the rebound model of immune memory.

bioRxiv · Oct 22, 2018Immunology

Aging Of Antiviral CD8+ Memory T Cells Fosters Increased Survival, Metabolic Adaptations And Lymphoid Tissue Homing

B. Davenport, J. Eberlein, V. van der Heide, K. Jhun, T. Nguyen, F. Victorino, A. Trotta, J. Chipuk, Z. Yi, W. Zhang, E. Clambey, D. K. Scott, D. Homann

This study shows that aging of antiviral CD8+ memory T cells leads to increased survival, metabolic adaptations, and lymphoid tissue homing, enhancing their recall response capabilities.

bioRxiv · Sep 22, 2017Immunology