Author

E. Crooks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D'Addabbo· 2 shared A. Thomas· 2 shared J. Allen· 2 shared J. M. Binley· 2 shared K. Osawa· 2 shared M. Crispin· 2 shared B. Korber· 1 shared E. Cale· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. D'Addabbo

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Impact of Glycan Depletion, Glycan Debranching and Increased Glycan Charge on HIV-1 Neutralization Sensitivity and Immunogenicity

A. D'Addabbo, T. Tong, E. Crooks, K. Osawa, J. Xu, A. Thomas, J. Allen, M. Crispin, J. M. Binley

This study evaluates glycoengineered HIV-1 trimers to enhance bNAb recognition, finding that B4GalT1+ST6GalT1 modifications increase antibody titers in infected donors but reduce vaccine-induced neutralizing antibodies.

Glycobiology · Aug 8, 2024Peer-reviewedImmunology

Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens

J. M. Binley, E. Crooks, F. Almanza, A. D'Addabbo, E. Duggan, J. Zhang, K. Wagh, H. Mou, J. Allen, A. Thomas, K. Osawa, B. Korber, Y. Tsybovsky, E. Cale, J. Nolan, , L. Verkoczy

This paper engineers HIV-1 envelope trimers with enhanced V2 and fusion peptide neutralization sensitivity for vaccine development.

bioRxiv · Jul 20, 2021Immunology