Author

L. Verkoczy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

J. Zhang· 3 shared A. Newman· 2 shared B. F. Haynes· 2 shared B. H. Hahn· 2 shared D. R. Burton· 2 shared J. Allen· 2 shared K. Wagh· 2 shared M. Crispin· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersImmunology

J. Zhang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A germline-targeting chimpanzee SIV envelope glycoprotein elicits a new class of V2-apex directed cross-neutralizing antibodies

F. Bibollet-Ruche, R. M. Russell, W. Ding, W. Liu, Y. Li, K. Wagh, D. Wrapp, R. Habib, A. N. Skelly, R. S. Roark, S. Sherrill-Mix, S. Wang, J. Rando, E. Lindemuth, K. Cruickshank, , B. H. Hahn

This study identifies a new class of V2-directed cross-neutralizing antibodies targeting a cryptic epitope in occluded-open HIV and SIV Env trimers.

bioRxiv · Oct 18, 2022Immunology

B cells discriminate HIV-1 Envelope protein affinities by sensing antigen binding association rates

M. A. Hossain, K. Anasti, B. Watts, K. Cronin, A. P. Kane, R. J. Edwards, D. Easterhoff, J. Zhang, W. Rountree, Y. Ortiz, L. Verkoczy, M. Reth, S. M. Alam

This study investigates how B cells distinguish HIV-1 Env proteins based on binding kinetics rather than equilibrium dissociation constants.

bioRxiv · Jan 14, 2022 · PreprintImmunology

Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens

J. M. Binley, E. Crooks, F. Almanza, A. D'Addabbo, E. Duggan, J. Zhang, K. Wagh, H. Mou, J. Allen, A. Thomas, K. Osawa, B. Korber, Y. Tsybovsky, E. Cale, J. Nolan, , L. Verkoczy

This paper engineers HIV-1 envelope trimers with enhanced V2 and fusion peptide neutralization sensitivity for vaccine development.

bioRxiv · Jul 20, 2021Immunology

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

R. Andrabi, J. Pallesen, J. Allen, G. Song, J. Zhang, N. de Val, G. Gegg, K. Porter, C.-Y. Su, M. Pauthner, A. Newman, H. Bouton-Vervelle, F. Garces, I. A. Wilson, M. Crispin, , D. R. Burton

The paper describes the structure of a chimpanzee SIV Env trimer and shows it induces HIV V2-specific neutralizing antibodies in mice.

bioRxiv · Nov 1, 2018Immunology