Author

K. Osawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D'Addabbo· 2 shared A. Thomas· 2 shared E. Crooks· 2 shared J. Allen· 2 shared J. M. Binley· 2 shared M. Crispin· 2 shared B. Korber· 1 shared C.-H. Juan· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. D'Addabbo

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Author profile →

3 papers

Recent·Most cited

Impact of Glycan Depletion, Glycan Debranching and Increased Glycan Charge on HIV-1 Neutralization Sensitivity and Immunogenicity

A. D'Addabbo, T. Tong, E. Crooks, K. Osawa, J. Xu, A. Thomas, J. Allen, M. Crispin, J. M. Binley

This study evaluates glycoengineered HIV-1 trimers to enhance bNAb recognition, finding that B4GalT1+ST6GalT1 modifications increase antibody titers in infected donors but reduce vaccine-induced neutralizing antibodies.

Glycobiology · Aug 8, 2024Peer-reviewedImmunology

Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens

J. M. Binley, E. Crooks, F. Almanza, A. D'Addabbo, E. Duggan, J. Zhang, K. Wagh, H. Mou, J. Allen, A. Thomas, K. Osawa, B. Korber, Y. Tsybovsky, E. Cale, J. Nolan, , L. Verkoczy

This paper engineers HIV-1 envelope trimers with enhanced V2 and fusion peptide neutralization sensitivity for vaccine development.

bioRxiv · Jul 20, 2021Immunology

Population genetic structure in the insular Ryukyu flying fox, Pteropus dasymallus

S.-F. Chen, C.-H. Juan, S. Rossiter, T. Kinjo, D. Fukui, K. Kawai, S. M. Tsang, M. J. Veluz, N.-H. Jang-Liaw, K. Osawa, W.-Y. Ko, M. Izawa

The paper analyzes genetic structure and diversity in the Ryukyu flying fox, finding isolation-by-distance and subdivision due to oceanic barriers, suggesting separate management of island subgroups.

bioRxiv · Mar 5, 2020Ecology