Author

E. D. Goddard-Borger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

S. J. Williams· 4 shared J. Li· 3 shared J. P. Lingford· 3 shared A. John· 2 shared G. J. Davies· 2 shared M. A. Jarva· 2 shared M. Sharma· 2 shared N. E. Scott· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersBiochemistry

S. J. Williams

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A broad-spectrum α-glucosidase of glycoside hydrolase family 13 from Marinovum sp., a member of the Roseobacter clade

J. Li, J. W.- Y. Mui, B. M. da Silva, D. E. V. Pires, D. B. Ascher, N. Madiedo Soler, E. D. Goddard-Borger, S. J. Williams

The paper identifies and characterizes a broad-spectrum α-glucosidase from Marinovum sp., revealing its unexpected activity on various disaccharides rather than sulfosugars.

bioRxiv · Mar 31, 2023 · PreprintBiochemistry

Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum

J. Li, M. Sharma, R. W. Meek, A. Alhifthi, Z. Armstrong, N. Madiedo Soler, M. Lee, E. D. Goddard-Borger, J. N. Blaza, G. J. Davies, S. J. Williams

This paper reports the cryo-EM structure and kinetics of sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum, revealing its cofactor usage and catalytic mechanism in sulfolactate synthesis.

bioRxiv · Mar 13, 2023 · PreprintBiochemistry

Identification of levoglucosan degradation pathways in bacteria and sequence similarity network analysis

A. Kaur, N. E. Scott, M. Herisse, E. D. Goddard-Borger, S. J. Pidot, S. J. Williams

The paper identifies two bacteria capable of degrading levoglucosan and analyzes their genome and proteome to understand the degradation pathway and related enzymes.

bioRxiv · Jan 28, 2023Microbiology

Structural basis of substrate recognition and catalysis by fucosyltransferase 8

M. A. Jarva, M. Dramicanin, J. P. Lingford, R. Mao, A. John, K. Jarman, R. W. Grinter, E. D. Goddard-Borger

This study determines the structural basis of substrate recognition and catalysis by FUT8 through crystal structures and simulations, revealing conformational changes and dimerization roles in substrate binding.

bioRxiv · Feb 14, 2020Biochemistry

A sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum bv. trifolii SRDI565

J. Li, R. Epa, J. P. Lingford, N. Scott, D. Skoneczny, M. Sharma, A. J. Snow, E. D. Goddard-Borger, G. J. Davies, M. J. McConville, S. J. Williams

This paper identifies a sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum that allows growth on sulfoquinovose, producing sulfolactate and contributing to bacterial persistence in soil.

bioRxiv · Dec 17, 2019Microbiology

Trefoil factors share a lectin activity that defines their role in mucus

M. A. Jarva, J. P. Lingford, A. John, N. E. Scott, E. D. Goddard-Borger

This study identifies trefoil factors as divalent lectins that bind GlcNAc--1,4-Gal disaccharides, contributing to mucus viscoelasticity through non-covalent glycoprotein cross-linking.

bioRxiv · Nov 29, 2019Biochemistry