Author

E. D. Hawkins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

I. Y. Kong· 2 shared J. M. Murphy· 2 shared L. Whitehead· 2 shared A. J. Murphy· 1 shared A. J. Vince· 1 shared A. L. Samson· 1 shared A. T. Papenfuss· 1 shared A. V. Jacobsen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

I. Y. Kong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Divergent roles for caspase-8 and MLKL in high-fat diet induced obesity and NAFLD in mice

H. Tye, S. A. Conos, T. M. Djajawi, N. Abdoulkader, I. Y. Kong, H. L. Kaummon, V. K. Narayana, M. Speir, T. A. Gottschalk, J. Emery, D. S. Simpson, C. Hall, A. J. Vince, S. Russo, R. Crawley, , K. Lawlor

This study investigates the distinct roles of caspase-8 and MLKL in high-fat diet-induced obesity and NAFLD in mice, showing that MLKL contributes to disease independently of inflammation.

bioRxiv · Mar 14, 2023Immunology

RNA decay defines the therapeutic response to transcriptional perturbation in leukaemia

I. Todorovski, B. Feran, Z. Fan, S. Gadipally, D. Yoannidis, I. Y. Kong, S. Bjelosevic, M. Zethoven, E. D. Hawkins, K. J. Simpson, G. Mir Arnau, A. T. Papenfuss, R. W. Johnstone, S. J. Vervoort

The paper shows that mRNA decay rates determine the effectiveness of transcriptional inhibitors in leukemia, with short-lived mRNAs being more responsive and long-lived ones being modulated by RNA-binding proteins.

bioRxiv · Apr 6, 2022 · PreprintCancer Biology

A toolbox for imaging RIPK1, RIPK3 and MLKL in mouse and human cells

A. L. Samson, C. Fitzgibbon, K. M. Patel, J. M. Hildebrand, L. Whitehead, J. S. Rimes, A. V. Jacobsen, C. R. Horne, X. J. Gavin, S. N. Young, K. L. Rogers, E. D. Hawkins, J. M. Murphy

This paper provides validated antibodies for detecting RIPK1, RIPK3, and MLKL in mouse and human cells, showing that methanol fixation is better than paraformaldehyde for immunofluorescence.

bioRxiv · Oct 26, 2020Cell Biology