Author

M. Speir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Murphy· 1 shared A. J. Vince· 1 shared A. Traven· 1 shared C. Hall· 1 shared C. Simm· 1 shared D. P. De Souza· 1 shared D. S. Simpson· 1 shared D. Shasha· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. J. Murphy

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Author profile →

2 papers

Recent·Most cited

Divergent roles for caspase-8 and MLKL in high-fat diet induced obesity and NAFLD in mice

H. Tye, S. A. Conos, T. M. Djajawi, N. Abdoulkader, I. Y. Kong, H. L. Kaummon, V. K. Narayana, M. Speir, T. A. Gottschalk, J. Emery, D. S. Simpson, C. Hall, A. J. Vince, S. Russo, R. Crawley, , K. Lawlor

This study investigates the distinct roles of caspase-8 and MLKL in high-fat diet-induced obesity and NAFLD in mice, showing that MLKL contributes to disease independently of inflammation.

bioRxiv · Mar 14, 2023Immunology

Candida auris evades innate immunity by using metabolic strategies to escape and kill macrophages while avoiding antimicrobial inflammation

H. C. Weerasinghe, C. Simm, T. Djajawi, I. Tedja, T. L. Lo, D. Shasha, N. Mizrahi, F. A. B. Olivier, M. Speir, K. E. Lawlor, R. Ben-Ami, A. Traven

This study shows Candida auris evades macrophage immunity through metabolic strategies that prevent antimicrobial responses and allow survival.

bioRxiv · Feb 28, 2023 · PreprintMicrobiology