Mechanisms involved in follistatin-induced hypertrophy and increased insulin action in skeletal muscle
X. Han, L. L. V. Moller, E. De Groote, K. K. N. Bojsen-Moller, J. Davey, C. Henriquez-Olguin, Z. Li, J. R. Knudsen, T. E. Jensen, S. Madsbad, P. Gregorevic, E. A. Richter, L. Sylow
This study shows that follistatin overexpression in muscle improves insulin-stimulated glucose uptake and protein synthesis, and that circulating follistatin increases after bariatric surgery, suggesting its role in insulin sensitivity.
bioRxiv · May 24, 2019Physiology