Brilacidin, a novel antifungal agent against Cryptococcus neoformans
C. Diehl, C. F. Pinzan, P. A. de Castro, E. Delbaje, L. G. Carnero, E. Sanchez-Leon, K. Bhalla, J. W. Kronstad, D.-g. Kim, T. L. Doering, S. Alkhazraji, N. N. Mishra, A. S. Ibrahim, M. Yoshimura, L. A. V. Isuhuayla, , G. H. Goldman
This paper identifies brilacidin as a novel antifungal agent effective against Cryptococcus neoformans, showing it reduces fungal survival in macrophages and potentiates existing antifungals.
bioRxiv · Apr 10, 2024 · PreprintMicrobiology