Author

E. Holden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Croft· 1 shared A. Orville· 1 shared A. Quigley· 1 shared B. Clough· 1 shared C. Jager· 1 shared D. Scott· 1 shared E. M. Adriaenssens· 1 shared E. M. Darby· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiophysics

A. Croft

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Differential development of antibiotic resistance and virulence between Acinetobacter species

E. M. Darby, R. A. Moran, E. Holden, T. Morris, F. Harrison, B. Clough, R. S. McInnes, L. Schneider, E. M. Frickel, M. A. Webber, J. M. A. Blair

This study compares antibiotic resistance and virulence between Acinetobacter lwoffii and A. baumannii, finding A. lwoffii has fewer resistance genes, more DNA defense systems, and reduced ability to develop resistance.

bioRxiv · Dec 1, 2023 · PreprintMicrobiology

Collateral sensitivity increases the efficacy of a rationally designed bacteriophage combination to control Salmonella enterica

L. Acton, H. Pye, G. Thilliez, R. Rafal, M. Matthews, K. Turner, M. Yasir, E. Holden, H. Al-Khanaq, M. Webber, E. M. Adriaenssens, R. A. Kingsley

This study identifies host susceptibility and resistance factors for Salmonella enterica infected by bacteriophages SPLA1a and SPLA5b, showing that their combination reduces phage resistance emergence.

bioRxiv · Sep 19, 2023 · PreprintMicrobiology

The adaptability of the ion binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF.

R. Lithgo, M. Hanzevacki, G. Harris, J. Kamps, E. Holden, J. L. Benesch, C. Jager, A. Croft, J. Hobman, A. Orville, A. Quigley, S. Carr, D. Scott

This study shows SilF, a periplasmic chaperone, binds both Ag(I) and Cu(I) with similar affinities, suggesting Gram-negative bacteria use an existing Cu(I) detox system for Ag(I) resistance.

bioRxiv · Mar 31, 2023Biophysics