J. M. A. Blair

This study compares antibiotic resistance and virulence between Acinetobacter lwoffii and A. baumannii, finding A. lwoffii has fewer resistance genes, more DNA defense systems, and reduced ability to develop resistance.

This study shows non-antibiotic pharmaceuticals inhibit E. coli growth at environmental concentrations without promoting cross-resistance to antibiotics.

This study shows that efflux pump inactivation in Salmonella changes membrane potential and physiology, affecting metabolism and antibiotic resistance.

This paper shows that Pseudomonas aeruginosa increases the susceptibility of Candida albicans to amphotericin B in dual species biofilms by inducing oxidative stress and downregulating detoxification enzymes.

This paper identifies AdeIJK as the ancestral RND efflux system in Acinetobacter by analyzing RND pump distribution across 63 species and developing a method to predict RND proteins.

The paper identifies critical residues in the periplasmic adaptor protein AcrA that influence substrate recognition and efflux through RND transporters in Salmonella.

This paper shows that disrupting disulfide bond formation in Gram-negative bacteria sensitizes them to antibiotics by impairing resistance proteins.

This study shows that efflux pumps only limit drug accumulation in actively growing cells, while envelope permeability is the main factor in stationary phase.

The paper shows AcrE can form a functional efflux pump with AcrD in Salmonella, demonstrating interchangeability with AcrA and identifying conserved binding sites for efflux inhibition.