Author

G. Harris

Purdue University West Lafayette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Croft· 1 shared A. J. Lloyd· 1 shared A. Orville· 1 shared A. Quigley· 1 shared A. S. Punekar· 1 shared Anas AljabbariiD· 1 shared Arezoo M. ArdekaniiD· 1 shared C. G. Dowson· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiophysics

A. Croft

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identifying differential effects from eleven mixing techniques on mRNA lipid nanoparticle physicochemistry and biological performance

Titania Bethiana, Anas Aljabbari, Y. Li, Harsa Mitra, Mojhdeh Baghbanbashi, G. Harris, Sophia R. Dasaro, Faezeh Masoomi, Frank S. Vago, Samuel Hartzler, Marxa Leão Figueiredo, Lauren Ann Metskas, Pavlos P. Vlachos, Arezoo M. Ardekani, Yoon Yeo, Kurt D. Ristroph

The paper compares the effects of eleven mixing techniques on mRNA lipid nanoparticle physicochemistry and biological performance, finding significant differences in particle properties and performance across methods.

bioRxiv · Nov 7, 2025 · PreprintBioengineering

The adaptability of the ion binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF.

R. Lithgo, M. Hanzevacki, G. Harris, J. Kamps, E. Holden, J. L. Benesch, C. Jager, A. Croft, J. Hobman, A. Orville, A. Quigley, S. Carr, D. Scott

This study shows SilF, a periplasmic chaperone, binds both Ag(I) and Cu(I) with similar affinities, suggesting Gram-negative bacteria use an existing Cu(I) detox system for Ag(I) resistance.

bioRxiv · Mar 31, 2023Biophysics

Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase

R. Cain, R. Salimaraj, A. S. Punekar, D. Bellini, C. W. G. Fishwisk, L. Czapleski, D. J. Scott, G. Harris, C. G. Dowson, A. J. Lloyd, D. I. Roper

The paper identifies small molecule inhibitors that selectively target bacterial seryl-tRNA synthetases over human homologues using structure-based drug discovery.

bioRxiv · Mar 22, 2019Biochemistry