Author

E. Holland

The University of Sydney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bohm· 1 shared A. Gerber· 1 shared Abigail Dennis· 1 shared Anne Elizabeth CustiD· 1 shared Antonia L. PritchardiD· 1 shared Aravind Sankar· 1 shared C. Binding· 1 shared C. Chen· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Bohm

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Large distant deletion disrupts CDKN2A enhancer and predisposes to melanoma

Peter A. Johansson, Kelly M. Brooks, Jane M. Palmer, Vaishnavi Nathan, Mai Xu, Jessica L. Scales, Rebecca Hennessey, E. Holland, Mark Harland, S Hutchison, Pui Ying Chan, Aravind Sankar, Sophie Papiernik, Abigail Dennis, Rohit Thakur, , Antonia L. Pritchard

The paper identifies a large distant deletion in DMRTA1 upstream of CDKN2A that predisposes to melanoma by disrupting regulatory sequences and reducing p16 expression.

medRxiv · May 18, 2026 · PreprintGenetic & Genomic Medicine

Functional genomic analysis of adult and pediatric brain tumor isolates

P. Hoellerbauer, M. Biery, S. Arora, Y. Rao, E. Girard, K. Mitchell, P. Dighe, M. Kufeld, D. Kuppers, J. Herman, E. Holland, L. Soroceanu, N. Vitanza, J. Olson, J. Pritchard, P. PADDISON

This study identifies shared and unique gene dependencies between adult and pediatric brain tumor isolates using CRISPR screens and machine learning models.

bioRxiv · Jan 5, 2023 · PreprintCancer Biology

Olverembatinib inhibits SARS-CoV-2-Omicron variant-mediated cytokine release

M. Chan, E. Holland, T. Gujral

This paper shows that Olverembatinib inhibits cytokine release caused by the SARS-CoV-2 Omicron variant in human PBMCs, suggesting it as a potential treatment for severe COVID-19.

bioRxiv · Feb 7, 2022 · PreprintImmunology

Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM

A. Bohm, J. DePetro, C. Binding, A. Gerber, N. Chahley, M. Ware, K. Thomas, S. Bukhari, C. Chen, E. Chahley, C. Grisdale, N. D. Berger, S. Lawn, Y. Yu, R. Wong, , G. Cairncross

This study develops a mouse model of glioblastoma (GBM) that replicates its genomic landscape and early stages, enabling research into prevention and treatment strategies.

bioRxiv · Nov 9, 2019 · PreprintCancer Biology