Author

J. Pritchard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Biochemistry· 1 Cancer Biology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. M. Gardner· 1 shared A. Mukundan· 1 shared A. P. Hinck· 1 shared A. S. Jaeger· 1 shared C. S. Hinck· 1 shared C. Schoenherr· 1 shared D. Brown· 1 shared D. Castaneda· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperPlant Biology

A. M. Gardner

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts

S. E. White, T. A. Schwartze, A. Mukundan, C. Schoenherr, S. P. Singh, M. van Dinther, K. T. Cunningham, M. P. J. White, T. Campion, J. Pritchard, C. S. Hinck, P. ten Dijke, G. Inman, R. M. Maizels, A. P. Hinck

This paper shows TGM6, a helminth protein, mimics TGF-β binding to TβRII to inhibit TGF-β signaling in fibroblasts but not T cells.

bioRxiv · Dec 22, 2023 · PreprintBiochemistry

Gain without pain: Adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vector

A. S. Jaeger, J. Marano, K. Riemersma, D. Castaneda, E. Pritchard, J. Pritchard, E. K. Bohm, J. J. Bacenzas, S. L. O'Connor, J. Weger-Lucarelli, T. C. Friedrich, M. Aliota

This study shows that ZIKV adapts to vertebrate hosts with increased virulence without reducing its ability to transmit via mosquitoes.

bioRxiv · Mar 20, 2023Microbiology

Functional genomic analysis of adult and pediatric brain tumor isolates

P. Hoellerbauer, M. Biery, S. Arora, Y. Rao, E. Girard, K. Mitchell, P. Dighe, M. Kufeld, D. Kuppers, J. Herman, E. Holland, L. Soroceanu, N. Vitanza, J. Olson, J. Pritchard, P. PADDISON

This study identifies shared and unique gene dependencies between adult and pediatric brain tumor isolates using CRISPR screens and machine learning models.

bioRxiv · Jan 5, 2023 · PreprintCancer Biology

The role of migration in mutant evolution in fragmented populations

J. Kreger, D. Brown, N. Komarova, D. Wodarz, J. Pritchard

This study investigates how migration affects mutant distribution in fragmented populations, showing that migration alters probability distributions and can sustain mutant numbers in small demes.

bioRxiv · Jun 9, 2021 · PreprintEvolutionary Biology

Is photosynthetic enhancement sustained through three years of elevated CO2 in a 175 year old oaks?

A. M. Gardner, D. S. Ellsworth, K. Y. Crous, J. Pritchard, R. A. Mackenzie

This study measures sustained photosynthetic enhancement in mature oak trees under elevated CO2 over three years without photosynthetic downregulation.

bioRxiv · Dec 16, 2020 · PreprintPlant Biology

Rapid evolution of the human mutation spectrum

K. Harris, J. Pritchard

The paper reports differences in mutational spectra across species and human populations, identifying a recent mutation rate change in Europeans.

bioRxiv · Apr 25, 2017Evolutionary Biology