E. J. G. Peterman

IFT cargo and motors associate sequentially with IFT trains to enter cilia

The paper uses single-molecule imaging to show that IFT components associate sequentially with IFT trains in C. elegans cilia, revealing their transport dynamics and the role of kinesin-II in axonemal organization.

Classifying directed and diffusive transport in short, noisy single-molecule trajectories with wMSD

This paper introduces wMSDc, a classifier to distinguish directed and diffusive transport in short, noisy single-molecule trajectories, showing superior performance compared to existing methods.

Differentiated dynamic response in C. elegans chemosensory cilia

The paper studies how C. elegans chemosensory cilia respond to different chemical stimuli using microfluidics and fluorescence microscopy, revealing distinct dynamic responses in IFT and neuronal activity.

TRPV channel OCR-2 is distributed along C. elegans chemosensory cilia by diffusion in a local interplay with intraflagellar transport

The paper shows OCR-2, a TRPV channel, redistributes along C. elegans cilia via diffusion and IFT after chemical exposure, revealing their dynamic interplay.

Supercoiling DNA optically

This paper introduces a single-molecule assay using dual-trap optical tweezers to rapidly generate and study negatively supercoiled DNA with force spectroscopy and fluorescence imaging.

One-dimensional sliding assists σ70-dependent promoter binding by Escherichia coli RNA polymerase

This study uses single-molecule imaging to show Escherichia coli RNA polymerase σ70 holoenzyme performs one-dimensional sliding on DNA during promoter search, even at high RNAP concentrations.