Author

E. J. Wagner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. C. Raimer· 1 shared A. D. Ebert· 1 shared A. G. Matera· 1 shared A. I. Lamond· 1 shared A. M. Spring· 1 shared B. Al-Rawashdeh· 1 shared B. Merriman· 1 shared B. Reversade· 1 shared

Activity by Year

2016-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. C. Raimer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly

L. G. Mascibroda, M. Shboul, N. D. Elrod, L. Colleaux, H. Hamamy, K.-L. Huang, N. J. Peart, M. K. Singh, H. Lee, B. Merriman, J. N. Jodoin, L. A. Lee, B. Al-Rawashdeh, O. Ababneh, M. El-Khateeb, , E. J. Wagner

This study identifies mutations in INTS13 causing a ciliopathy by disrupting Integrator complex assembly and ciliogenesis.

bioRxiv · Jul 20, 2020 · PreprintBiochemistry

Self-oligomerization regulates stability of Survival Motor Neuron (SMN) protein isoforms by sequestering an SCFSlmb degron

K. M. Gray, K. A. Kaifer, D. Baillat, Y. Wen, T. R. Bonacci, A. D. Ebert, A. C. Raimer, A. M. Spring, S. ten Have, J. J. Glascock, K. Gupta, G. D. Van Duyne, M. J. Emanuele, A. I. Lamond, E. J. Wagner, , A. G. Matera

The paper identifies SCFSlmb as a regulator of SMN protein stability through a degron, showing that self-oligomerization stabilizes SMN isoforms and mitigates SMA severity.

bioRxiv · Sep 30, 2016Biochemistry