Author

S. ten Have

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. C. Raimer· 1 shared A. D. Ebert· 1 shared A. G. Matera· 1 shared A. I. Lamond· 1 shared A. M. Spring· 1 shared C. L. Lorson· 1 shared D. Baillat· 1 shared E. J. Wagner· 1 shared

Activity by Year

2016-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. C. Raimer

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Author profile →

2 papers

Recent·Most cited

The Ndc80 complex targets Bod1 to human mitotic kinetochores

K. Schleicher, S. ten Have, I. M. Porter, J. R. Swedlow

This paper shows that the Ndc80 complex recruits Bod1 to mitotic kinetochores, regulating PP2A-B56 activity and Ndc80 phosphorylation to maintain chromosome-spindle attachments.

bioRxiv · Apr 27, 2017Cell Biology

Self-oligomerization regulates stability of Survival Motor Neuron (SMN) protein isoforms by sequestering an SCFSlmb degron

K. M. Gray, K. A. Kaifer, D. Baillat, Y. Wen, T. R. Bonacci, A. D. Ebert, A. C. Raimer, A. M. Spring, S. ten Have, J. J. Glascock, K. Gupta, G. D. Van Duyne, M. J. Emanuele, A. I. Lamond, E. J. Wagner, , A. G. Matera

The paper identifies SCFSlmb as a regulator of SMN protein stability through a degron, showing that self-oligomerization stabilizes SMN isoforms and mitigates SMA severity.

bioRxiv · Sep 30, 2016Biochemistry