Hypoxia-induced Complement Component 3 Promotes Aggressive Tumor Growth in the Glioblastoma Microenvironment
R. Rosberg, K. I. Smolag, J. Sjolund, E. Johansson, C. Bergelin, J. Wahlden, V. Pantazopoulou, C. Ceberg, K. Pietras, A. M. Blom, A. Pietras
This study identifies hypoxia-induced complement component 3 (C3) as a driver of aggressive glioblastoma growth by promoting cell proliferation and radio-resistance.
bioRxiv · Jan 28, 2024Cancer Biology