Author

E. Kristianto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. K. Fletcher· 2 shared J. Jurczyluk· 2 shared M. A. Munoz· 2 shared M. J. Rogers· 2 shared O. P. Skinner· 2 shared A. A. Robertson· 1 shared A. Simon· 1 shared C. M. Mulders-Manders· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPhysiology

E. K. Fletcher

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2 papers

Recent·Most cited

Increased core body temperature exacerbates defective protein prenylation in mouse avatars of mevalonate kinase deficiency

M. A. Munoz, O. P. Skinner, E. Masle-Farquhar, J. Jurczyluk, Y. Xiao, E. K. Fletcher, E. Kristianto, M. P. Hodson, S. I. O'Donoghue, S. Kaur, R. Brink, D. Zahra, E. K. Deenick, K. Perry, A. A. Robertson, , M. J. Rogers

This study shows that increased body temperature worsens protein prenylation defects in mouse models of mevalonate kinase deficiency, suggesting temperature as a trigger for inflammation.

bioRxiv · Feb 28, 2022 · PreprintPhysiology

Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages

M. J. Rogers, M. A. Munoz, E. K. Fletcher, O. P. Skinner, J. Jurczyluk, E. Kristianto, M. Hodson, S. Sun, F. H. Ebetino, D. R. Croucher, P. M. Hansbro, J. R. Center

This study shows bisphosphonates inhibit the mevalonate pathway in macrophages, enhancing immune responses to bacterial endotoxin in the lung.

bioRxiv · Aug 9, 2021Pharmacology & Toxicology