Author

E. L. Paine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. R. Mackay· 2 shared J. J. Skalicky· 2 shared K. S. Ullman· 2 shared W. I. Sundquist· 2 shared A. Devine· 1 shared C. D. Paul· 1 shared C. P. Hill· 1 shared D. M. Wenzel· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

D. R. Mackay

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Author profile →

3 papers

Recent·Most cited

The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission

E. L. Paine, J. J. Skalicky, F. G. Whitby, D. R. Mackay, K. S. Ullman, C. P. Hill, W. I. Sundquist

This study shows that CAPN7 interacts with IST1 at midbodies to regulate abscission and the NoCut checkpoint through proteolytic activity.

bioRxiv · Oct 18, 2022Biochemistry

Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission

D. M. Wenzel, D. R. Mackay, J. J. Skalicky, E. L. Paine, M. S. Miller, K. S. Ullman, W. I. Sundquist

This study maps the human MIT-ESCRT-III interactome, identifies new cofactors for cytokinetic abscission, and reveals their functional roles in abscission and regulation.

bioRxiv · Feb 9, 2022Biochemistry

Tissue architectural cues drive organ targeting of human tumor cells in zebrafish

C. D. Paul, K. Bishop, A. Devine, E. L. Paine, J. R. Staunton, S. M. Thomas, L. M. Miller Jenkins, N. Y. Morgan, R. Sood, K. Tanner

The paper shows human tumor cells preferentially colonize specific tissues in zebrafish based on vessel topography and integrin expression, revealing mechanisms of metastatic organ targeting.

bioRxiv · Jul 19, 2018Biophysics