K. S. Ullman

The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission

This study shows that CAPN7 interacts with IST1 at midbodies to regulate abscission and the NoCut checkpoint through proteolytic activity.

A Role for Nup153 in Nuclear Assembly Reveals Differential Requirements for Targeting of Nuclear Envelope Constituents

This study identifies Nup153's role in nuclear envelope formation, showing differential requirements for targeting of nuclear envelope proteins during nuclear reassembly.

Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission

This study maps the human MIT-ESCRT-III interactome, identifies new cofactors for cytokinetic abscission, and reveals their functional roles in abscission and regulation.

Abscission Checkpoint Bodies Reveal a New Facet of Abscission Checkpoint Control

The paper identifies cytoplasmic abscission checkpoint bodies (ACBs) that regulate cytokinetic abscission by delaying midbody machinery recruitment.

Systematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling

The paper identifies calcineurin (CN) substrates and interactors using a combination of experimental and computational methods, revealing novel roles for CN in regulating nuclear pore complex proteins.

A role for liquid-liquid phase separation in ESCRT-mediated nuclear envelope reformation.

This study shows how LEM2 uses liquid-liquid phase separation and ESCRT pathways to facilitate nuclear envelope reformation during mitotic exit.

A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability

This paper identifies a cancer-associated polymorphism in CHMP4C that disrupts the abscission checkpoint, leading to genome instability and increased cancer risk.

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells

This study identifies LEM2 and CHMP7 as conserved factors that recruit ESCRT-III proteins to the nuclear envelope during closure in fission yeast and human cells.