D. R. Mackay

The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission

This study shows that CAPN7 interacts with IST1 at midbodies to regulate abscission and the NoCut checkpoint through proteolytic activity.

A Role for Nup153 in Nuclear Assembly Reveals Differential Requirements for Targeting of Nuclear Envelope Constituents

This study identifies Nup153's role in nuclear envelope formation, showing differential requirements for targeting of nuclear envelope proteins during nuclear reassembly.

Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission

This study maps the human MIT-ESCRT-III interactome, identifies new cofactors for cytokinetic abscission, and reveals their functional roles in abscission and regulation.

Abscission Checkpoint Bodies Reveal a New Facet of Abscission Checkpoint Control

The paper identifies cytoplasmic abscission checkpoint bodies (ACBs) that regulate cytokinetic abscission by delaying midbody machinery recruitment.

Systematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling

The paper identifies calcineurin (CN) substrates and interactors using a combination of experimental and computational methods, revealing novel roles for CN in regulating nuclear pore complex proteins.