Author

E. Lummertz da Rocha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. S. Mansur· 2 shared A. A. Santos· 1 shared A. Bafica· 1 shared A. K. Shalek· 1 shared A. Morrot· 1 shared B. J. Ferguson· 1 shared C. B. Lorenzini· 1 shared C. C. Natale· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

D. S. Mansur

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Author profile →

3 papers

Recent·Most cited

PKR-mediated Stress Response Enhances Dengue and Zika Virus Replication

T. Ricciardi-Jorge, E. Lummertz da Rocha, E. Gonzalez-Kozlova, G. F. Rodrigues-Luiz, B. J. Ferguson, T. Sweeney, N. Irigoyen, D. S. Mansur

This study shows that PKR-mediated stress response enhances Dengue and Zika virus replication by co-opting the integrated stress response to promote viral mRNA translation.

bioRxiv · Apr 8, 2021Immunology

Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19

R. O. Formiga, F. C. Amaral, C. F. Souza, D. A. G. B. Mendes, C. W. S. Wanderley, C. B. Lorenzini, A. A. Santos, J. Antonia, L. F. Faria, C. C. Natale, N. M. Paula, P. C. S. Silva, F. R. Fonseca, L. Aires, N. Heck, , F. Spiller

This paper shows neuraminidase inhibitors reduce neutrophil overactivation in sepsis and COVID-19 by inhibiting sialic acid release and ROS production.

bioRxiv · Nov 12, 2020 · PreprintImmunology

Single-cell analysis reveals mechanisms of plasticity of leukemia initiating cells

V. Morris, W. Marion, T. Hughes, P. Sousa, P. Sensharma, Y. Pikman, M. Harris, A. K. Shalek, T. North, G. Q. Daley, E. Lummertz da Rocha, G. Rowe

The paper uses single-cell transcriptomics to show that leukemia initiating cells can convert between states, with MYC-driven oxidative phosphorylation controlling this plasticity.

bioRxiv · Apr 29, 2020 · PreprintCancer Biology