Author

E. M. Schraner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Eichwald· 4 shared C. Fraefel· 4 shared O. R. Burrone· 4 shared G. Papa· 3 shared A. Lkharrazi· 2 shared B. Vogt· 2 shared F. Arnoldi· 2 shared H. Büning· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMicrobiology

C. Eichwald

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The interferon-γ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way

S. O. Sutter, K. Tobler, M. Seyffert, A. Lkharrazi, J. Zöllig, E. M. Schraner, B. Vogt, H. Büning, C. Fraefel

The paper identifies IFI16 as a restriction factor for AAV2 transduction that acts independently of immune modulation by interfering with Sp1-dependent promoter activation.

bioRxiv · Jan 22, 2024 · PreprintMicrobiology

Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiency

S. O. Sutter, S. Jetzer, A. Lkharrazi, S. Pedersen, E. M. Schraner, B. Vogt, H. Büning, C. Fraefel

The paper shows that inducing autophagy with hyperosmotic sucrose enhances AAV2 transduction efficiency through a non-canonical pathway, distinct from the PI3K-III-dependent mechanism.

bioRxiv · Jan 8, 2024 · PreprintMicrobiology

Recruitment of TRiC chaperonin in rotavirus viroplasms directly associates with virus replication.

J. Vetter, G. Papa, K. Tobler, M. Kley, M. Myers, M. Wiesendanger, E. M. Schraner, O. R. Burrone, C. Fraefel, C. Eichwald

This study identifies TRiC chaperonin as a component of rotavirus viroplasms essential for dsRNA synthesis and virus replication.

bioRxiv · Dec 13, 2022 · PreprintMicrobiology

A recombinant rotavirus harboring a spike protein with a heterologous peptide reveals a novel role of VP4 in viroplasm stability

G. Papa, J. Vetter, M. Seyffert, K. Gunasekera, G. De Lorenzo, M. Wiesendanger, E. M. Schraner, J.-L. Reymond, C. Fraefel, O. R. Burrone, C. Eichwald

This paper engineers a recombinant rotavirus with a VP4-BAP tag, showing VP4's role in viroplasm stability and replication fitness.

bioRxiv · May 13, 2021 · PreprintMicrobiology

Recombinant rotaviruses rescued by reverse genetics reveal the role of NSP5 hyperphosphorylation in the assembly of viral factories

G. Papa, L. Venditti, F. Arnoldi, E. M. Schraner, C. Potgieter, A. Borodavka, C. Eichwald, O. R. Burrone

This study uses reverse genetics to generate recombinant rotaviruses with NSP5 mutations, revealing that NSP5 hyperphosphorylation is essential for viroplasm assembly and viral replication.

bioRxiv · Jul 8, 2019Microbiology

The guanine nucleotide exchange factor GBF1 participates in rotavirus replication

J. L. Martinez, F. Arnoldi, E. M. Schraner, C. Eichwald, D. Silva-Ayala, E. Lee, E. Sztul, O. R. Burrone, S. Lopez, C. F. Arias

This study shows that GBF1 is required for rotavirus replication by facilitating VP7 and NSP4 processing and virion assembly.

bioRxiv · Apr 29, 2019Microbiology