Author

E. P. Papapetrou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. G. Kotini· 1 shared A. Plotnikov· 1 shared A. R. Pine· 1 shared B. Geiger· 1 shared B. Haim· 1 shared C. S. Leslie· 1 shared H. Yuan· 1 shared I. Grosheva· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. G. Kotini

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Author profile →

2 papers

Recent·Most cited

Rock inhibitors target SRSF2 leukemia by disrupting cell mitosis and nuclear morphology

M. Su, T. Fleisher, I. Grosheva, M. B. Horev, M. Olszewska, B. Haim, A. Plotnikov, S. Carvalho, Y. Moskovitz, M. Minden, N. Chapal-Ilani, E. P. Papapetrou, N. Dezorella, T. Cheng, N. Kaushansky, , L. I. Shlush

This study identifies ROCK inhibitors as effective targeting agents for SRSF2 mutant leukemia by disrupting mitosis and nuclear morphology in vitro and in xenograft models.

bioRxiv · Feb 15, 2022 · PreprintCancer Biology

Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of leukemia

T. Wang, A. R. Pine, J. Wesely, H. Yuan, L. Zamparo, A. G. Kotini, C. S. Leslie, E. P. Papapetrou

This study uses sequential CRISPR gene editing in human iPSCs to model clonal evolution in AML, showing progressive dysplasia and identifying therapeutic vulnerabilities.

Cell Stem Cell · Jun 1, 2021Peer-reviewedCancer Biology