Author

J. Keegan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:flow cytometry· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

D. A. Rao· 2 shared J. A. Lederer· 2 shared M. Gutierrez-Arcelus· 2 shared T. M. Eisenhaure· 2 shared T. Sasaki· 2 shared Y. Cao· 2 shared A. Arazi· 1 shared A. B. Pernis· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

D. A. Rao

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Author profile →

3 papers

Recent·Most cited

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

A. Horisberger, A. Griffith, J. Keegan, A. Arazi, J. Pulford, E. Murzin, K. Howard, B. Hancock, A. Fava, T. Sasaki, T. Ghosh, J. Inamo, R. Beuschel, Y. Cao, K. Preisinger, , Accelerating Medicines Pa

The paper identifies three immunologically distinct groups in lupus nephritis patients based on blood immunophenotyping, correlating with histopathology, treatment response, and renal outcomes.

bioRxiv · Jan 14, 2024Immunology

Longitudinal immune cell profiling in early systemic lupus erythematosus

T. Sasaki, S. Bracero, J. Keegan, L. Chen, Y. Cao, E. Stevens, Y. Qu, G. Wang, J. Nguyen, S. E. Alves, J. A. Lederer, K. H. Costenbader, D. A. Rao

This study tracks immune cell changes in early systemic lupus erythematosus using mass cytometry and identifies longitudinal shifts in Tfh cells and CXCL10.

bioRxiv · Nov 8, 2021Immunology

High dimensional analyses of cells dissociated from cryopreserved synovial tissue

L. T. Donlin, D. A. Rao, K. Wei, K. Slowikowski, M. J. McGeachy, J. D. Turner, N. Meednu, F. Mizoguchi, M. Gutierrez-Arcelus, D. J. Lieb, J. Keegan, K. Muskat, J. Hillman, C. Rozo, E. Ricker, , M. B Brenner

This paper establishes a protocol for dissociating cryopreserved synovial tissue to obtain viable cells with preserved transcriptomes and surface markers, enabling high-dimensional analysis of rheumatoid arthritis pathology.

bioRxiv · Mar 19, 2018Immunology