Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors
B. Chen, E. T. McKinley, A. J. Simmons, M. A. Ramirez, X. Zhu, A. N. Southard-Smith, N. O. Markham, Q. Sheng, J. Drewes, Y. Xu, C. N. Heiser, Y. Zhou, F. Revetta, L. D. Berry, W. Zheng, , K. Lau
The paper creates a single-cell atlas of colorectal pre-cancerous polyps, identifying distinct molecular programs in adenomas and sessile serrated lesions and their associations with CRC subtypes.
bioRxiv · Jan 11, 2021Cancer Biology