Q. Sheng

Cytokine and Chemokine Receptor Profiles in Adipose Tissue Vasculature Unravel Endothelial Cell Responses in HIV

This study examines cytokine and chemokine receptor expression in adipose tissue endothelial cells of HIV-positive individuals, identifying receptor differences and their potential role in vascular dysfunction.

M1 Macrophage-Related Genes Model for NSCLC Immunotherapy Response Prediction

This study develops a model using M1 macrophage-related genes to predict immunotherapy response and prognosis in advanced NSCLC patients.

CD3+ T-cell: CD14+monocyte complexes are dynamic and increased with HIV and glucose intolerance

The paper identifies increased CD3+ T-cell:CD14+ monocyte complexes in diabetes and HIV, associated with inflammation and metabolic changes.

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

The paper creates a single-cell atlas of colorectal pre-cancerous polyps, identifying distinct molecular programs in adenomas and sessile serrated lesions and their associations with CRC subtypes.

Novel enzyme for dimethyl sulfide-releasing in bacteria reveals a missing route in the marine sulfur cycle

The paper identifies a novel ATP-dependent DMSP lysis pathway in bacteria, revealing a new route in the marine sulfur cycle through the enzyme AcoD.

SETD2 regulates the methylation of translation elongation factor eEF1A1 in clear cell renal cell carcinoma

The paper investigates how SETD2 mutations in clear cell renal cell carcinoma affect protein methylation and translation, finding dysregulated translation linked to poor patient outcomes.

Inhibition of miR-22-3p reduces kidney disease associated with systemic lupus erythematosus

This study shows that inhibiting miR-22-3p reduces lymphocyte accumulation and kidney disease in a mouse model of systemic lupus erythematosus.