Author

C. N. Heiser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

K. Lau· 3 shared Q. Liu· 2 shared A. Calindi· 1 shared A. J. Simmons· 1 shared A. N. Southard-Smith· 1 shared B. Chen· 1 shared B. R. Helm· 1 shared C. L. Sears· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

K. Lau

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3 papers

Recent·Most cited

Single-cell transcriptomics reveals heterogenous thymic dendritic cell subsets with distinct functions and requirements for thymocyte-regulated crosstalk

J. Srinivasan, C. R. Moore, A. Calindi, B. R. Helm, Y. Yang, J. F. Moore, H. J. Selden, C. N. Heiser, Q. Liu, K. Lau, L. I. R. Ehrlich

The paper identifies seven thymic conventional dendritic cell subsets and their distinct functional roles and dependencies on thymocyte subsets for homeostasis and activation.

bioRxiv · Dec 18, 2023 · PreprintImmunology

Multiplexed 3D atlas of state transitions and immune interactions in colorectal cancer

J.-R. Lin, S. Wang, S. Coy, Y.-A. Chen, C. Yapp, M. A. Tyler, M. Nariya, C. N. Heiser, K. Lau, S. Santagata, P. K. Sorger

This study uses multiplexed 3D imaging and machine learning to analyze colorectal cancer morphology and immune interactions, revealing molecular gradients and cell state transitions.

bioRxiv · Mar 31, 2021Cancer Biology

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

B. Chen, E. T. McKinley, A. J. Simmons, M. A. Ramirez, X. Zhu, A. N. Southard-Smith, N. O. Markham, Q. Sheng, J. Drewes, Y. Xu, C. N. Heiser, Y. Zhou, F. Revetta, L. D. Berry, W. Zheng, , K. Lau

The paper creates a single-cell atlas of colorectal pre-cancerous polyps, identifying distinct molecular programs in adenomas and sessile serrated lesions and their associations with CRC subtypes.

bioRxiv · Jan 11, 2021Cancer Biology