Author

J. L. Franklin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:virus· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

R. J. Coffey· 3 shared Q. Liu· 2 shared A. Atucha· 1 shared A. H. Wright· 1 shared A. Hebert-Hache· 1 shared A. J. Simmons· 1 shared A. M. Scott· 1 shared A. N. Southard-Smith· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCancer Biology

R. J. Coffey

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

miR-100 and miR-125b Contribute to Enhanced 3D Growth and Invasiveness and can be Functionally Transferred to Silence Target Genes in Recipient Cells

H. M. Nelson, S. Qu, L. Huang, M. Shameer, K. C. Corn, S. N. Chapman, N. L. Luthcke, S. A. Schuster, L. A. Turnbull, L. L. Guy, X. Liu, K. C. Vickers, Q. Liu, J. L. Franklin, A. Weaver, , J. G. Patton

This study identifies miR-100 and miR-125b as regulators of 3D growth and invasiveness in cancer cells, showing they can be transferred extracellularly to silence target genes in recipient cells.

bioRxiv · Jan 16, 2024 · PreprintCancer Biology

Detection of EGFR and its Activity State in Plasma CD63-EVs from Glioblastoma Patients: Rapid Profiling using an Anion Exchange Membrane Sensor

N. Maniya, S. Kumar, J. L. Franklin, J. N. Higginbotham, A. M. Scott, H. K. Gan, R. J. Coffey, S. Senapati, H.-C. Chang

This paper introduces a novel immunoassay for detecting EGFR and its activity state in plasma CD63-EVs from glioblastoma patients, achieving high sensitivity and specificity for early detection.

bioRxiv · Oct 16, 2023 · PreprintCancer Biology

NYUS.2: an Automated Machine Learning Prediction Model for the Large-scale Real-time Simulation of Grapevine Freezing Tolerance in North America

H. Wang, G. D. Moghe, A. P. Kovaleski, M. Keller, T. E. Martinson, A. H. Wright, J. L. Franklin, A. Hebert-Hache, C. Provost, M. Reinke, A. Atucha, M. G. North, P. Helwi, M. Centinari, J. P. Londo

The paper develops NYUS.2, an automated machine learning model for real-time simulation of grapevine freezing tolerance in North America, outperforming previous models with lower error.

bioRxiv · Aug 21, 2023Plant Biology

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

B. Chen, E. T. McKinley, A. J. Simmons, M. A. Ramirez, X. Zhu, A. N. Southard-Smith, N. O. Markham, Q. Sheng, J. Drewes, Y. Xu, C. N. Heiser, Y. Zhou, F. Revetta, L. D. Berry, W. Zheng, , K. Lau

The paper creates a single-cell atlas of colorectal pre-cancerous polyps, identifying distinct molecular programs in adenomas and sessile serrated lesions and their associations with CRC subtypes.

bioRxiv · Jan 11, 2021Cancer Biology

VIBRIO CHOLERAE ADAPTS TO SESSILE AND MOTILE LIFESTYLES BY CYCLIC DI-GMP REGULATION OF CELL SHAPE

N. L. Fernandez, N. T. Nhu, B. Y. Hsueh, J. L. Franklin, Y. S. Dufour, C. M. Waters

This study shows that V. cholerae regulates cell shape via c-di-GMP, linking curvature to biofilm formation and motility.

bioRxiv · Apr 15, 2020Microbiology