ImmunologybioRxiv
CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade
S. N. Bossio, C. Abrate, J. Tosello Boari…·C. L. Montes
The paper identifies CD39+ CD4+ T cells in tumors with exhaustion and cytotoxic traits, showing their expansion with CTLA-4 blockade and association with better survival in breast cancer.