Author

L. Almada

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Gruppi· 3 shared C. L. Montes· 3 shared C. G. Beccaria· 2 shared F. Fiocca Vernengo· 2 shared J. Tosello Boari· 2 shared M. Gorosito Serran· 2 shared A. A. Mangaonkar· 1 shared A. Buradkar· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

A. Gruppi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tissue damage during acute Trypanosoma cruzi infection is associated with reduced reparative regulatory T cell response and can be attenuated by early interleukin-33 administration.

S. Boccardo, C. Rodriguez, C. L. A. Furlan, C. P. Abrate, L. Almada, C. M. Gimenez, M. A. S. Concepcion, P. Skewes-Cox, S. P. S. Rao, C. L. Montes, A. Gruppi, E. V. A. Rodriguez

This study shows that reduced trTregs during T. cruzi infection correlates with tissue damage, and early IL-33 treatment increases trTregs and reduces damage.

bioRxiv · Feb 15, 2024 · PreprintImmunology

PD-L1hi plasmablasts limit the T cell response during the acute phase of parasite infections

M. Gorosito Serran, F. Fiocca Vernengo, L. Almada, C. G. Beccaria, P. F. Canete, J. Rocco Alegre, J. Tosello Boari, M. C. Ramello, E. Wehrens, Y. Cai, E. I. Zuniga, C. L. Montes, E. V. Acosta Rodriguez, I. A. Cockburn, C. G. Vinuesa, A. Gruppi

The paper identifies PD-L1hi plasmablasts that suppress T cell responses during acute parasite infections.

bioRxiv · Jun 10, 2020 · PreprintImmunology

RAS mutations drive proliferative chronic myelomonocytic leukemia via activation of a novel KMT2A-PLK1 axis

R. M. Carr, D. Vorobyev, T. Lasho, D. L. Marks, E. J. Tolosa, A. Vedder, L. Almada, A. Yurchenko, I. Padioleau, B. Alver, G. Coltro, M. Binder, S. L. Safgren, I. Horn, X. You, , M. M. Patnaik

This study identifies RAS mutations as drivers of proliferative CMML through a novel KMT2A-PLK1 axis, showing PLK1 inhibition can improve disease outcomes in patient-derived xenografts.

bioRxiv · Dec 23, 2019 · PreprintCancer Biology

CD8+ T cell immunity is compromised by anti-CD20 treatment and rescued by IL-17A

F. Fiocca Vernengo, C. G. Beccaria, C. L. Araujo Furlan, J. Tosello Boari, L. Almada, M. Gorosito Serran, Y. Gazzoni, C. L. Montes, E. Acosta Rodriguez, A. Gruppi

This paper shows anti-CD20 treatment reduces CD8+ T cell immunity in a Trypanosoma cruzi infection model, and IL-17A can partially restore it.

bioRxiv · May 20, 2019Immunology