Author

E. Y. D. Chua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Research Focus:imputation· 1

Frequent Co-Authors

B. Carragher· 2 shared C. S. Potter· 2 shared E. T. Eng· 2 shared J. H. Mendez· 2 shared L. M. Alink· 2 shared V. Serbynovskyi· 2 shared A. Cheng· 1 shared A. de Marco· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersBiophysics

B. Carragher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 29, 2023

Square beams for optimal tiling in TEM

E. Y. D. Chua, L. M. Alink, M. Kopylov…·A. de Marco

This paper introduces a square electron beam for TEM to improve tiling and reduce exposure unevenness in cryo-EM imaging.

DOI 10.1101/2023.07.29.551095

electronic health recordsexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 23, 2022

Fully Automated Multi-Grid Cryo-EM Screening using Smart Leginon

A. Cheng, P. Kim, H. Kuang…·A. J. Noble

Smart Leginon automates cryo-EM grid screening, reducing operator time from 6 hours to <10 minutes and improving throughput.

DOI 10.1101/2022.07.23.501225

cryo-EMdeep learning

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 16, 2022

Vitrocam: A simple low cost Vitrobot camera for assessing grid quality

E. Y. D. Chua, V. Serbynovskyi, R. Gheorghita…·B. Carragher

The paper introduces Vitrocam, a low-cost camera to assess cryo-EM grid quality during sample preparation by imaging the Vitrobot process.

DOI 10.1101/2022.06.16.496351

imagingexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivMay 20, 2022

Structural basis for substrate selection by the SARS-CoV-2 replicase

B. F. Malone, J. K. Perry, P. D. B. Olinares…·S. A. Darst

This study uses cryo-EM to reveal how the SARS-CoV-2 RTC discriminates between natural NTPs and the antiviral remdesivir triphosphate, providing insights for antiviral design.

DOI 10.1038/s41586-022-05664-3

virusstructural biology

𝕏 PostBluesky