Edgardo A Aguilar

This study shows FLASH radiotherapy reduces lymphocyte apoptosis and prevents immunosuppression by modulating the Chk1-STAT3 pathway in a preclinical model.

This paper introduces an automated workflow for analyzing histopathological images of the intestinal microcolony survival assay, achieving accuracy comparable to experts with reduced human error and time.

This study shows proton FLASH radiotherapy reduces long-term musculoskeletal and marrow toxicities in juvenile mice, suggesting its potential for pediatric osteosarcoma treatment.

This study shows FLASH radiotherapy preserves lymphocytes and increases immune cell infiltration in tumors, potentially improving antitumor immune responses.

This study evaluates how varying radiation beam parameters affect gastrointestinal toxicity and tumor response in mice, finding that high dose per pulse and ultra-high dose rate independently reduce toxicity while maintaining tumor control.