Steven Hsesheng Lin

This study identifies ALDH2 as a direct target of colchicine, showing it suppresses radiation-induced senescence and atherosclerosis by modulating mitochondrial redox and macrophage function.

This study shows FLASH radiotherapy reduces lymphocyte apoptosis and prevents immunosuppression by modulating the Chk1-STAT3 pathway in a preclinical model.

SuperSurv provides a unified R package for building, evaluating, and interpreting ensemble survival models with right-censored data, using SHAP values and IPCW Brier risk for weighting.

This study compares acute gastrointestinal toxicity from synchrotron-based proton and linac-based electron ultra-high dose rate irradiation in mice, finding higher toxicity with proton FLASH compared to conventional and electron treatments.

This study evaluates how varying radiation beam parameters affect gastrointestinal toxicity and tumor response in mice, finding that high dose per pulse and ultra-high dose rate independently reduce toxicity while maintaining tumor control.