Author

Eli Abel

Nationwide Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Aparna VenugopalaniD· 1 shared Estelle Cormet‐BoyakaiD· 1 shared Gongbo Guo· 1 shared Jacob T. StackiD· 1 shared Karen L Kanke· 1 shared Ma Suu· 1 shared Mark E. HesteriD· 1 shared Rachael E. RayneriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Aparna VenugopalanORCID

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1 paper

Recent·Most cited

Single-Stranded DNA with Internal Base Modifications Mediates Highly Efficient Gene Insertion in Primary Cells

Karen L Kanke, Rachael E. Rayner, Eli Abel, Aparna Venugopalan, Ma Suu, Jacob T. Stack, Reza Nouri, Gongbo Guo, Tatyana A. Vetter, Estelle Cormet‐Boyaka, Mark E. Hester, Sriram Vaidyanathan

The paper demonstrates that chemically modified ssDNA (eDNA) significantly improves gene insertion efficiency in primary cells compared to unmodified ssDNA, achieving therapeutic levels in clinically relevant loci.

bioRxiv · Feb 1, 2024 · PreprintMolecular Biology