Author

Aparna Venugopalan

Nationwide Children's HospitalORCID 0000-0003-1830-3168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Eli Abel· 1 shared Estelle Cormet‐BoyakaiD· 1 shared Gongbo Guo· 1 shared Jacob T. StackiD· 1 shared Karen L Kanke· 1 shared Ma Suu· 1 shared Mark E. HesteriD· 1 shared Rachael E. RayneriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Eli Abel

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 1, 2024

Single-Stranded DNA with Internal Base Modifications Mediates Highly Efficient Gene Insertion in Primary Cells

Karen L Kanke, Rachael E. Rayner, Eli Abel…·Sriram Vaidyanathan

The paper demonstrates that chemically modified ssDNA (eDNA) significantly improves gene insertion efficiency in primary cells compared to unmodified ssDNA, achieving therapeutic levels in clinically relevant loci.

1 citation

humanCRISPR screen

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