Author
The Ohio State UniversityORCID 0000-0001-9839-384XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Mostafa M. Eltobgy, Mohamed M. Shamseldin, Owen D. Whitham…·Amal O. Amer
This study shows that Caspase-11 worsens severe SARS-CoV-2 by increasing inflammation and reducing CD8 T-cell immunity, but its removal improves viral clearance and survival.
Heba M. Amer, Mohamed M. Shamseldin, Sarah Faber…·Amal O. Amer
This study uses an automated behavioral system and transcriptomic analysis to identify cognitive impairments in mice with long COVID, finding similar transcriptomic changes to humans.
Jacob T. Stack, Rachael E. Rayner, Reza Nouri…·Sriram Vaidyanathan
This study shows that inhibiting DNA repair pathways with AZD7648 improves gene insertion efficiency in airway stem cells for CFTR correction, but may introduce toxicity.
Marisa R. Joldrichsen, Eunsoo Kim, Haley E. Steiner…·Prosper N. Boyaka
The paper shows that loss of Paneth cells in mice alters gut ILC subsets and increases weight gain on a high-fat diet.
Karen L Kanke, Rachael E. Rayner, Eli Abel…·Sriram Vaidyanathan
The paper demonstrates that chemically modified ssDNA (eDNA) significantly improves gene insertion efficiency in primary cells compared to unmodified ssDNA, achieving therapeutic levels in clinically relevant loci.