Author

Ellen Lavorando

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Hsin‐Yao TangiD· 2 shared Kathy Fange LiuiD· 2 shared Maria Saraí Mendoza-FigueroaiD· 2 shared Amber M. YanasiD· 1 shared Anthony Yulin Chen· 1 shared Charles Antony AiD· 1 shared Dawn M. CaroneiD· 1 shared Heidi E. ElashaliD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Hsin‐Yao TangORCID

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2 papers

Recent·Most cited

Defining the impact of rRNA processing on nucleolar organization and function

Maria Saraí Mendoza-Figueroa, Ellen Lavorando, Yulia Gonskikh, Charles Antony A, Heidi E. Elashal, Anthony Yulin Chen, Hsin‐Yao Tang, Dawn M. Carone, Vikram R. Paralkar, Kathy Fange Liu

This study shows that impaired 5'ETS pre-rRNA cleavage disrupts nucleolar organization, leading to mislocalization of RNA and proteins, and broader nuclear architecture changes.

bioRxiv · Oct 19, 2025 · PreprintMolecular Biology

Mutant forms of DDX3X with diminished catalysis form hollow condensates that exhibit sex-specific regulation

Michael C. Owens, Hui Shen, Amber M. Yanas, Maria Saraí Mendoza-Figueroa, Ellen Lavorando, Xiaoyu Wei, Him Shweta, Hsin‐Yao Tang, Yale E. Goldman, Kathy Fange Liu

This study shows that specific DDX3X mutants form hollow condensates, impairing catalytic activity and interacting differently with WT DDX3X and DDX3Y, which may explain sex-specific disease biases.

bioRxiv · Mar 19, 2023 · PreprintMolecular Biology