Author

Erin N. Shirk

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Bianca Cruz PachaneiD· 2 shared Kenneth Whitaker WitweriD· 2 shared Olesia A. GololobovaiD· 2 shared Suzanne E. QueeniD· 2 shared Bess W. Carlson· 1 shared Blanca V. RodrigueziD· 1 shared Chan-Hyun NaiD· 1 shared Heloísa Sobreiro Selistre-de-AraújoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

Bianca Cruz PachaneORCID

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2 papers

Recent·Most cited

Human endogenous retrovirus envelope proteins alter extracellular vesicle cellular interactions and biodistribution

Zach Troyer, Miranda Soumakis, Erin N. Shirk, Olesia A. Gololobova, Sarah Márquez, Martina Fabiano, Bianca Cruz Pachane, Taekyung Ryu, Chan-Hyun Na, Natalie Castell, Isabella M. Baumann, Suzanne E. Queen, Joseph L. Mankowski, Kenneth Whitaker Witwer

This study engineers extracellular vesicles with Syncytin-1 to alter their biodistribution and shows improved persistence and organ targeting in non-human primates.

bioRxiv · May 5, 2026 · PreprintBioengineering

An ex vivo and in vitro investigation of extracellular vesicle interactions with B cells of Macaca nemestrina and humans

Bianca Cruz Pachane, Blanca V. Rodriguez, Erin N. Shirk, Olesia A. Gololobova, Bess W. Carlson, Suzanne E. Queen, Loren D. Erickson, Heloísa Sobreiro Selistre-de-Araújo, Kenneth Whitaker Witwer

The paper investigates how extracellular vesicles interact with B cells in nonhuman primates and humans, showing uptake via endocytosis and membrane fusion, and highlights potential strategies to modulate EV-B cell interactions.

bioRxiv · Feb 12, 2025 · PreprintMolecular Biology